PARP Inhibitor With 177Lu-DOTA-Octreotate PRRT in Patients With Neuroendocrine Tumours (PARLuNET)
PARLuNET is a phase 1 dose-escalation study designed to evaluate the safety and tolerability of talazoparib (PARP Inhibitor) in combination with 177Lu-DOTA-Octreotate peptide receptor radionuclide therapy (PRRT) in patients with metastatic pancreatic and mid gut neuroendocrine tumour (NET).
Patients will receive 1 cycle of 177Lu-DOTA-Octreotate alone followed by 3 cycles of 177Lu-DOTA-Octreotate combined with 5 days of talazoparib.
This trial is looking to recruit 24 patients and if you would like to know if you are eligible, please ask your doctor to assess the inclusion criteria listed at PARP Inhibitor With 177Lu-DOTA-Octreotate PRRT in Patients With Neuroendocrine Tumours – Full Text View – ClinicalTrials.gov
Contact
Grace Kong 03 8559 5000 or NMResearch@petermac.org
Research Manager: 03 8559 6602
Recruiting: NMResearch@petermac.org
Locations
Australia, Victoria
Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia
Sponsors and Collaborators
Peter MacCallum Cancer Centre, Australia
